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Sephadex LH-20

sephadex(R) LH-20 for chromatography

CAS: 9041-37-6

Molecular Formula: C9H8N2O3S

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Sephadex LH-20 - Names and Identifiers

Name sephadex(R) LH-20 for chromatography
Synonyms Sephadex LH-20
lipophilic sephadex
sephadex(R) LH-20 for chromatography
CAS 9041-37-6

Sephadex LH-20 - Physico-chemical Properties

Molecular FormulaC9H8N2O3S
Molar Mass224.23642
Storage ConditionRoom Temprature
UseUse biochemical research. Dextran gel is a bead-like cross-linked dextran that contains a large amount of hydroxyl groups and is easy to swell in water and electrolyte solutions. G-type dextran gels have various degrees of crosslinking. Therefore, their swelling and fractional separation ranges are also different. Sepandex G-10 and G-25 sugar gels are used in aqueous solutions. If an organic solvent is used as the mobile phase, Sepandex G needs to be converted into hydroxypropyl dextran gels that can swell in organic solvents through hydroxypropylation. The product at this time is Sepandex LH-20. Dextran gels have different particle sizes. Ultrafine grade dextran gels are used for column and thin layer chromatography that require extremely high resolution. Crude and intermediate gels are used in laboratory and industrial preparation processes to obtain higher flow rates at lower pressures. Dextran gel LH-20 can be used to separate cholesterol, fatty acids, hormones, vitamins, natural products, etc.

Sephadex LH-20 - Risk and Safety

Safety Description22 - Do not breathe dust.
WGK Germany3
HS Code29400090

Sephadex LH-20 - Upstream Downstream Industry

Downstream ProductsGoserelin

Sephadex LH-20 - Reference

Reference
Show more
1. Deng Zhaowei, Yang Jiguo. Ultrasonic-microwave synergistic extraction of procyanidins from litchi peel and analysis of its high polymer composition [J]. China food additive, 2020, v.31;No.194(04):85-94.
2. Yan Hongpeng, Zhang Caixia, Zhao Suqing, etc. Preliminary Study on extraction and purification of ciguatoxin [J]. Progress in Marine Sciences, 2012, 30(003):408-415.
3. Li Q, Guo Y, Yu X, Liu W, Zhou L. Protectivemechanism of rhubarb thraquone glycosides in rats with cerebral ischaemia-reperfusion injury: interactions between medicine and intestinal flora. Chin Med. 2020 Jun 5;15:60. doi: 10.1186/s13020-020-00341-x.
4. Yang Liu, Juan Li, Zhi Li, Xing Tang, Zhenzhong Zhang, Pharmacokinetics of a ternary conjugate based pH-responsive 10-HCPT prodrug nano-micelle delivery system, Asian Journal of Pharmaceutical Sciences, Volume 12, Issue 6, 2017, Pages 542-549 ISSN 1818-08
5. Liu, Yang et al. “A pH-responsive prodrug delivery system of 10-HCPT for controlled release and tumor targeting." International journal of nanomedicine vol. 12 2227-2242. 22 Mar. 2017, doi:10.2147/IJN.S125849
6. [IF=6.598] Yang Liu et al."Pharmacokinetics of a ternary conjugate based pH-responsive 10-HCPT prodrug nano-micelle delivery system."Asian J Pharm Sci. 2017 Nov;12:542
7. [IF=6.4] Yang Liu et al."A pH-responsive prodrug delivery system of 10-HCPT for controlled release and tumor targeting."Int J Nanomed. 2017; 12: 2227-2242
8. [IF=7.514] Wenyang Tao et al."Extraction and identification of proanthocyanidins from the leaves of persimmon and loquat."Food Chem. 2022 Mar;372:130780
9. [IF=5.455] Qiuying Li et al."Protective mechanism of rhubarb anthraquinone glycosides in rats with cerebral ischaemia-reperfusion injury: interactions between medicine and intestinal flora."Chin Med-Uk. 2020 Jun 5;15:60
10. [IF=4.411] Di Liu et al."Two New Apotirucallane-Type Triterpenoids from the Pericarp of Toona sinensis and Their Ability to Reduce Oxidative Stress in Rat Glomerular Mesangial Cells Cultured under High-Glucose Conditions."Molecules. 2020 Jan;25(4):801
11. [IF=3.307] Fang-Zhou Li et al."Bioprospecting of a novel endophytic Bacillus velezensis FZ06 from leaves of Camellia assamica: Production of three groups of lipopeptides and the inhibition against food spoilage microorganisms."J Biotechnol. 2020 Nov;323:42
12. [IF=2.19] Jie Yang et al."Multiple responses optimization of antioxidative components extracted from distiller's grains using response surface methodology and identify their chemical compositions."J Food Process Pres. 2021 Nov;45(11):e15885

Sephadex LH-20 - Introduction

sephadex(R) LH-20 for chromatography is a packing used in chromatographic separations, also known as Sephadex(R) LH-20. It is cross-linked by dextran (Dextran) and 2,3-dimethyl digitalis digitalis digitalis glycoside (Digitoxin). Its main features include:

1. High porosity and porosity: sephadex(R) LH-20 for chromatography has a large number of pores, which makes it able to adsorb target substances and effectively separate them in chromatography.

2. wide applicability: sephadex(R) LH-20 for chromatography is suitable for various chromatographic techniques, such as gel chromatography, gel permeation chromatography and ion exchange chromatography. It is often used for the purification and separation of natural products.

3. Low background: sephadex(R) LH-20 for chromatography has a high adsorption capacity, but the background signal is low, making the separation results more accurate.

The method for preparing sephadex(R) LH-20 for chromatography is to first prepare dextran and conduct a cross-linking reaction with 2,3-dimethyl digitalis digitalis digitalis glycoside. The cross-linked product is then comminuted and prepared into a form suitable for chromatographic operations.

For safety information, the following are general considerations:

1. Avoid contact with skin, eyes or respiratory system. Please wear personal protective equipment such as gloves, glasses and masks when using.

2. During operation, avoid inhaling or swallowing the substance. The working environment should be well ventilated to avoid dust generation.

3. When storing, please store the sephadex(R) LH-20 for chromatography in a dry, cool and dark place, avoiding high temperature and fire.
Last Update:2024-04-09 20:02:46
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Sephadex LH-20 Visit Supplier Webpage Request for quotation
CAS: 9041-37-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Yuanye Bio-Technology Co., Ltd.
Featured ProductsSpot supply
Product Name: Sephadex LH-20 Visit Supplier Webpage Request for quotation
CAS: 9041-37-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
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Product Name: Sephadex LH-20 Request for quotation
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Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: Sephadex LH-20 Visit Supplier Webpage Request for quotation
CAS: 9041-37-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
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MedChemExpress (MCE)
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SKYRUN INDUSTRIAL CO.,LTD
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Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: sephadex(R) LH-20 for chromatography Request for quotation
CAS: 9041-37-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
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View History
Sephadex LH-20
FMOC-NHNH2 HCL
Human TH Protein, His Tag
4-Methoxybenzoic acid hydrazide
Upadacitinib Impurity 24
BroMoacetyl br
MTF-BOC
Hydroxycarbamine
107-82-4
5472-68-4
Downstream Products for Sephadex LH-20
Goserelin
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